AP17686PU-N PSME2 / REG-beta (C-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse PSME2 / REG-beta

AP17686PU-N

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  • AP17686PU-N

Product Description for PSME2 / REG-beta

Rabbit anti Human, Mouse PSME2 / REG-beta.
Properties: (C-term)
Product is tested for Western blot / Immunoblot.

Properties for PSME2 / REG-beta

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms 11S regulator complex subunit beta, Activator of multicatalytic protease subunit 2, PA28b, PA28beta, Proteasome activator, Proteasome activator 28 subunit beta, Proteasome activator complex subunit 2
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9UL46
Immunogen:
KLH conjugated synthetic peptide selected from the C-terminal region of human PSME2
GeneID:
5721
Property C-term
Application ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
Immunohistochemistry on Paraffin embedded sections 1/50 - 1/100
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME2 is the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon.
Concentration lot specific
General Readings
  1. Conticello,S.G., Curr. Biol. 13 (22), 2009-2013 (2003)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Saturated Ammonium Sulfate (SAS) precipitation
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid purified Ig
Specificity
Specificity:
This antibody reacts to PSME2.
Species:
Human, Mouse.
Gene ID 5721

Accessory Products

Proteins and/or Positive Controls

Proteins for PSME2 / REG-beta (7 products)

Catalog No. Species Pres. Purity   Source  

PSME2 / REG-beta

PSME2 / REG-beta Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PSME2 / REG-beta (1-239, His-tag)

PSME2 / REG-beta Human Purified > 95 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

PSME2 / REG-beta (1-239, His-tag)

PSME2 / REG-beta Human Purified > 95 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

PSME2 / REG-beta

PSME2 / REG-beta Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PSME2 / REG-beta

PSME2 / REG-beta Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PSME2 / REG-beta

PSME2 / REG-beta Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PSME2 / REG-beta

PSME2 / REG-beta Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for PSME2 / REG-beta (2 products)

Catalog No. Species Pres. Purity   Source  

PSME2 293T Cell Transient Overexpression Lysate(Denatured)

PSME2 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PSME2 Lysate

Western Blot: PSME2 Lysate [NBL1-14908] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PSME2
  Novus Biologicals Inc.
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