AM32454PU-N PTPN7 / HEPTP antibody

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50 µl / €470.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human PTPN7 / HEPTP AFPK32

AM32454PU-N

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  • AM32454PU-N

Product Description for PTPN7 / HEPTP

Mouse anti Human PTPN7 / HEPTP AFPK32.
Presentation: Ig Fraction
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot, Paraffin Sections.

Properties for PTPN7 / HEPTP

Product Category Primary Antibodies
Target Category
Quantity 50 µl
Synonyms Hematopoietic protein-tyrosine phosphatase, Protein-tyrosine phosphatase LC-PTP, Tyrosine-protein phosphatase non-receptor type 7
Presentation Ig Fraction
Reactivity Hu
Applications E, P, WB
Clonality Monoclonal
Clone AFPK32
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P35236
Immunogen:
Recombinant Human PTPN7 purified from E. coli
GeneID:
5778
Application ELISA.
Immunohistochemistry on Paraffin Sections: 1/200.
Western Blot: 1/5000.
Background HePTP, a R7 non-receptor protein tyrosine phosphatase, has been shown to affect T cell receptor signaling. HePTP negatively regulates expression of MAP kinases Erk1, Erk2 and p38 by dephosphorylating the critical phosphorylated tyrosine residue in their activation loop. HePTP has also been suggested to mediate interactions between cAMP system and MAP-kinase cascade. Mice deficient in HePTP show enhanced activation of ERK after phorbol myristate acetate and anti-CD3-mediated T-cell receptor stimulation. HePTP is located on the chromosome region 1q32.1, which is known to be a site associated with chromosomal deletion in malignant lymphomas, where candidate tumor suppressor genes might be present.
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Ammonium Sulfate Precipitation
Buffer System:
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% Sodium Azide, and 50% Glycerol
State:
Liquid Ig fraction
Ig Fraction
Specificity
Specificity:
This antibody recognizes Human PTPN7 / HEPTP.

Accessory Products

Proteins and/or Positive Controls

Proteins for PTPN7 / HEPTP (7 products)

Catalog No. Species Pres. Purity   Source  

PTPN7 / HEPTP (transcript variant 1)

PTPN7 / HEPTP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PTPN7 / HEPTP (transcript variant 2)

PTPN7 / HEPTP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PTPN7 / HEPTP

PTPN7 / HEPTP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PTPN7 / HEPTP

PTPN7 / HEPTP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PTPN7 / HEPTP

PTPN7 / HEPTP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

PTPN7 / HEPTP

PTPN7 / HEPTP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

PTPN7 / HEPTP

PTPN7 / HEPTP Human
  Abnova Taiwan Corp.

Positive controls for PTPN7 / HEPTP (4 products)

Catalog No. Species Pres. Purity   Source  

PTPN7 293T Cell Transient Overexpression Lysate(Denatured)

PTPN7 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PTPN7 293T Cell Transient Overexpression Lysate(Denatured)

PTPN7 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PTPN7 Lysate

Western Blot: PTPN7 Lysate [NBL1-14977] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PTPN7
  Novus Biologicals Inc.

PTPN7 Lysate

Western Blot: PTPN7 Lysate [NBL1-14978] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PTPN7
  Novus Biologicals Inc.
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