discontinued

NB100-75302 PTPR Sigma antibody

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0.05 mg / €410.00

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Chicken anti Human PTPR Sigma

Product Description for PTPR Sigma

Chicken anti Human PTPR Sigma.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for PTPR Sigma

Product Category Primary Antibodies
Quantity 0.05 mg
Synonyms EC 3.1.3.48, PTPRS, PTPSigma, Protein Tyrosine Phosphatase Sigma, R-PTP-S, R-PTP-Sigma, Receptor-Type Tyrosine-Protein Phosphatase S, Receptor-Type Tyrosine-Protein Phosphatase Sigma
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Chicken
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q59FX6
Immunogen:
The immunogen for this antibody was a sequence from 330a.a. to 524a.a. from PTPRS(a 1948a.a. long protein)
GeneID:
5802
Application Western Blot, Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development., Western Blot
Background PTPRS belongs to the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. Interacts with LAR-interacting protein LIP.1.
Concentration 1 mg/ml
General Readings
  1. Hu,Y.F., Zhang,H.L., Cai,T., Harashima,S. and Notkins,A.L., et al. The IA-2 interactome
  2. Blanchetot,C., Tertoolen,L.G., Overvoorde,J. and den Hertog,J., et al. Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases
  3. Suarez Pestana,E., Tenev,T., Gross,S., Stoyanov,B., Ogata,M. and Bohmer,F.D. The transmembrane protein tyrosine phosphatase RPTPsigma modulates signaling of the epidermal growth factor receptor in A431 cells
  4. Wallace,M.J., Batt,J., Fladd,C.A., Henderson,J.T., Skarnes,W. and Rotin,D. Neuronal defects and posterior pituitary hypoplasia in mice lacking the receptor tyrosine phosphatase PTPsigma
  5. Elchebly,M., Wagner,J., Kennedy,T.E., Lanctot,C., Michaliszyn,E., Itie,A., Drouin,J. and Tremblay,M.L. Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma
  6. , Pulido R., Serra-Pages C., Tang M., Streuli M. The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.
  7. , Endo N., Rutledge S.J., Opas E.E., Vogel R., Rodan G.A., Schmidt A. Human protein tyrosine phosphatase-sigma: alternative splicing and inhibition by bisphosphonates.
  8. , Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., et al. The DNA sequence and biology of human chromosome 19.
  9. , Adachi M., Sekiya M., Arimura Y., Takekawa M., Itoh F., Hinoda Y., Imai K., Yachi A. Protein-tyrosine phosphatase expression in pre-B cell NALM-6.
  10. , Serra-Pages C., Medley Q.G., Tang M., Hart A., Streuli M. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Immunogen affinity purified
Buffer System:
No Preservative
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
PTPRS
Species:
Human
Gene ID 5802

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