AP53516PU-N PTPRN2 (N-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human PTPRN2

Product Description for PTPRN2

Rabbit anti Human PTPRN2.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for PTPRN2

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms IA-2beta, IAR, ICAAR, Islet cell autoantigen-related protein, KIAA0387, Phogrin, R-PTP-N2, Receptor-type tyrosine-protein phosphatase N2
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q92932
Immunogen:
Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 160-189aa) of human PTPRN2.
GeneID:
5799
Property N-term
Add. information Molecular Weight: 111271 Da
Application

Western blot: 1/100-1/500.
Enzyme immunoassay: 1/1000.

Background The protein encoded by the PTPRN2 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Concentration lot specific
General Readings Bailey, S.D., et al. Diabetes Care 33(10): 2250-2253 (2010)
Rose, J.E., et al. Mol. Med. 16 (7-8): 247-253 (2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5): 800-812 (2010)
Yoshida, T., et al. Int. J. Mol. Med. 25(4): 649-656 (2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5): 628-642 (2009)
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Purified through a Protein A column followed by peptide affinity purification
Buffer System:
PBS with 0.09% (W/V) Sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody recognizes PTPRN2 at N-term.
Gene ID 5799

Accessory Products

Proteins and/or Positive Controls

Proteins for PTPRN2 (4 products)

Catalog No. Species Pres. Purity   Source  

PTPRN2 (transcript variant 2)

PTPRN2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PTPRN2

PTPRN2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PTPRN2

PTPRN2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PTPRN2

PTPRN2 Human
  Abnova Taiwan Corp.

Positive controls for PTPRN2 (3 products)

Catalog No. Species Pres. Purity   Source  

PTPRN2 293T Cell Transient Overexpression Lysate(Denatured)

PTPRN2 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PTPRN2 overexpression lysate

PTPRN2 overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.

PTPRN 293T Cell Transient Overexpression Lysate(Denatured)

PTPRN 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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