AP13234PU-N PVR (C-term) antibody

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Rabbit anti Human PVR

Product Description for PVR

Rabbit anti Human PVR.
Properties: (C-term)
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for PVR

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms poliovirus receptor
Presentation Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PVR.
Property C-term
Application ELISA: 1/1,000.
Immunohistochemistry: 1/50 - 1/100.
Background The poliovirus receptor (PVR) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. PVR is involved in intercellular adhesion and its cytoplasmic domain may target endocytic vesicles to the microtubular network. The extracellular domain of PVR mediates cell attachment to the extracellular matrix molecule vitronectin, while its cytoplasmic domain interacts with the dynein light chain Tctex-1. PVR is a primate-restricted protein expressed during development in mesenchymal tissues and ventrally derived structures within the CNS. Its exact biological function remains to be determined; it is reported that PVR is aberrantly expressed in tumors of neuroectodermal origin.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration 0.25 mg/ml
General Readings
  1. Zibert, A., et al., J. Virol. 66(12):7368-7373 (1992).
  2. Koike, S., et al., Proc. Natl. Acad. Sci. U.S.A. 88(10):4104-4108 (1991).
  3. Koike, S., et al., EMBO J. 9(10):3217-3224 (1990).
  4. Mendelsohn, C.L., et al., Cell 56(5):855-865 (1989).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Buffer System:
PBS with 0.09% (W/V) sodium azide
Liquid purified Ig
This antibody reacts to PVR.

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