NBP1-00997 Rac1/2/3/CDC42 antibody

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Rabbit anti Human, Mouse, Rat Rac1/2/3/CDC42


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  • NBP1-00997

Product Description for Rac1/2/3/CDC42

Rabbit anti Human, Mouse, Rat Rac1/2/3/CDC42.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for Rac1/2/3/CDC42

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Add. information Research Areas: Cancer
Application ELISA, immunohistochemistry, Western Blot, This antibody is useful for the following applications and dilutions: ELISA 1:20000-1:40000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,, ELISA 1:20000-1:40000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,
Background A large number of low molecular weight, GTP binding proteins of the Ras superfamily have been identified. These proteins regulate many fundamental processes in all eukaryotic cells such as growth, vesicle traffic and cytoskeletal organization. Two proteins in this family, Rac 1 and Rac 2, are 92% identical and share GTP binding and GTP hydrolysis motifs with other members of the Ras superfamily. Rac 1 is expressed in a large number of different cell types. Rac 2 is primarily expressed only in myeloid cells and has been reported to be a regulatory component of the human neutrophil NADPH oxidase. Endogenous, hyperactive Rac3 is present in the highly proliferative human breast cancerderived cell lines and tumor tissues. Active Rac3 associates with two Rac effector proteins, p21-activated kinase (Pak) and c-Jun N-terminal kinase (JNK) and drives Pak and JNK kinase activities by two separate pathways.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
15mM Sodium Azide
Immunogen affinity purified
Aff - Purified
Human, Mouse, Rat

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