AM50507PU-N Radial Glial Cell Marker-2 antibody

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Mouse anti Mouse Radial Glial Cell Marker-2 RC2


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  • AM50507PU-N

Product Description for Radial Glial Cell Marker-2

Mouse anti Mouse Radial Glial Cell Marker-2 RC2.
Presentation: Purified
Product is tested for Frozen Sections.

Properties for Radial Glial Cell Marker-2

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Ms
Applications C
Clonality Monoclonal
Clone RC2
Host Mouse
Isotype IgM
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Embryonic rat brain.
Isotype control SM13P
Application Immunohistochemistry.
Background The monoclonal antibody Radial Glial Cell Marker-2, clone RC2 (RC2) was generated in mouse by conventional hybridoma methodology. The antigen recognized by RC2 is robust, allowing aldehyde fixation appropriate to high resolution light and electron microscopic analyses. From the neural tube stage of fetal development the antibody delineates throughout the central nervous system a subpopulation of neuroepithelial cells which have a radial bipolar morphology. RC2 also recognizes monopolar cell forms in the spinal cord and the cerebellum as early as E15, and in the dentate gyrus of the hippocampal formation from the day of birth. Monopolar forms in the cerebellum are inferred to be progenitors of Bergmann glia. The robustness of the antigen recognized by RC2 makes this probe a valuable tool to study the morphological transformations of the bipolar radial glia during their mitotic turnover. It also provides a sensitive stain for the study of the organization and the histogenetic role of the overall radial fiber system (3).
Concentration lot-specific
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Ammonium sulfate precipitation.
Buffer System:
PBS with 0.05% Sodium Azide
Liquid purified Ig fraction
Detects radial glial cell marker-2
Mouse. Other species have not been tested.

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