BP7034 Raf (c-Raf) antibody

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Rabbit anti Human, Mouse, Rat Raf (c-Raf)


Product Description for Raf (c-Raf)

Rabbit anti Human, Mouse, Rat Raf (c-Raf).
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Raf (c-Raf)

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

A sequence corresponding to the c-Raf protein surrounding the C-terminus of the protein
Application Western blot (0.2 to 2.0 µg/mL).
Immunocytochemistry (0.2 to 2.0 µg/mL).
Background c-Raf, also known as Raf-1, is a serine/threonine kinase which is activated by IL-3 Receptor, IGF-I, EGF, GM-CSF and other growth factors and mediates enhancement of IL-2 induction during T-cell activation. Oncogenic activation of c-Raf induces the expression of the epidermal growth factor. Activation of Raf by GTP-bound Ras causes phosphorylation of MEK, which leads to activation of MAPK/Erk Kinases. Deactivation of c-Raf occurs as a result of PKA inhibition of growth factors.
Concentration 2.17 mg/ml
Storage Store at -80 şC. Upon initial thawing, aliquot and store at -80 şC. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Immunoaffinity chromatography
Buffer System:
Phosphate buffer, pH 7.4. Carrier and preservative free.
Liquid Ig fraction
Aff - Purified
This antibody detects c-Raf.
Human, mouse, rat.

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