NB100-62713 Rat Lambda light chain antibody

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0.125 mg / €410.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Rat Rat Lambda light chain MARL-15

NB100-62713

Product Description for Rat Lambda light chain

Mouse anti Rat Rat Lambda light chain MARL-15.
Presentation: HRP
Product is tested for Enzyme Immunoassay.

Properties for Rat Lambda light chain

Product Category Primary Antibodies
Quantity 0.125 mg
Presentation HRP
Reactivity Rt
Applications E
Clonality Monoclonal
Clone MARL-15
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Rat lambda light chain
Application ELISA, This antibody is useful for ELISA, ELISA
Background All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Label:
HRP
Buffer System:
0.01% Thimerosal
Specificity
Specificity:
Recognises rat immunoglobulin lambda light chain. This shows no cross-reactivity to rat Ig heavy chains or to kappa light chain.
Species:
Rat

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