NB100-62713 Rat Lambda light chain antibody

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Mouse anti Rat Rat Lambda light chain MARL-15


Product Description for Rat Lambda light chain

Mouse anti Rat Rat Lambda light chain MARL-15.
Presentation: HRP
Product is tested for Enzyme Immunoassay.

Properties for Rat Lambda light chain

Product Category Primary Antibodies
Quantity 0.125 mg
Presentation HRP
Reactivity Rt
Applications E
Clonality Monoclonal
Clone MARL-15
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rat lambda light chain
Application ELISA, This antibody is useful for ELISA, ELISA
Background All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer System:
0.01% Thimerosal
Recognises rat immunoglobulin lambda light chain. This shows no cross-reactivity to rat Ig heavy chains or to kappa light chain.

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