discontinued

NB100-64787 Rat Lambda light chain antibody

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0.25 mg / €330.00

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Mouse anti Rat Rat Lambda light chain MARL-15

NB100-64787

Product Description for Rat Lambda light chain

Mouse anti Rat Rat Lambda light chain MARL-15.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for Rat Lambda light chain

Product Category Primary Antibodies
Quantity 0.25 mg
Presentation Aff - Purified
Reactivity Rt
Applications C, E, P, WB
Clonality Monoclonal
Clone MARL-15
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Rat lambda light chain
Application ELISA, Immunohistochemistry-Frozen, Western Blot, Immunohistochemistry-Frozen, ELISA and Western Blot, ELISA , Western Blot 1:500 - 1:1000, Immunohistochemistry-Frozen
Background All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain are present in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Affinity purified
Buffer System:
0.09% Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
Recognizes rat immunoglobulin lambda light chain. This shows no cross-reactivity to rat Ig heavy chains or to kappa light chain.
Species:
Rat

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