SM2096P Rat Lambda light chain antibody

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0.25 mg / €340.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Rat Rat Lambda light chain MARL-15


Product Description for Rat Lambda light chain

Mouse anti Rat Rat Lambda light chain MARL-15.
Presentation: Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Rat Lambda light chain

Product Category Primary Antibodies
Quantity 0.25 mg
Presentation Purified
Reactivity Rt
Applications C, E, WB
Clonality Monoclonal
Clone MARL-15
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Rat lambda light chain.
Spleen cells from immunised BALB/c mice were fused with cells of the rat PAI-O myeloma cell line.
Application ELISA.
Western Blot: 1/500-1/1000.
Immunohistochemistry on Frozen Sections.
Background All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
Concentration 1.0 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity Chromatography
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide
Liquid purified IgG fraction
This antibody recognizes immunoglobulin lambda light chain. This antibody shows no cross-reactivity to Ig heavy chains or to kappa light chain.

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