discontinued

AM01217PU-N Renal Cell Carcinoma antibody

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Search for all "Renal Cell Carcinoma"

0.2 mg / €310.00

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Mouse anti Human Renal Cell Carcinoma PN-15

AM01217PU-N

Product Description for Renal Cell Carcinoma

Mouse anti Human Renal Cell Carcinoma PN-15.
Presentation: Purified
Product is tested for Frozen Sections, Western blot / Immunoblot, Paraffin Sections.

Properties for Renal Cell Carcinoma

Product Category Primary Antibodies
Quantity 0.2 mg
Synonyms gp200
Presentation Purified
Reactivity Hu
Applications C, P, WB
Clonality Monoclonal
Clone PN-15
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Renal cortical tissue extract was used to immunize BALB/c mice.
Isotype control AM03110PU-N, SM12P
Application This antibody can be used for the differential diagnosis of carcinomas by Western blotting and
immunohistochemistry on frozen and paraffin-embedded tissues. Protease digestion prior to antibody incubation enhances staining of tissue sections.
Background This antibody reacts with a glycoprotein of 200 kDa present in proximal renal tubules. The antigen is a carbohydrate in nature and retained in formalin fixed paraffin embedded tissues. Other normal tissues that display the antigen include breast, parathyroid glands and epididymis. Among renal carcinomas, 93% of primary and 84% of metastatic carcinomas are positive for this antigen. Relatively few other tumor types are positive: breast cancers, teratocarcinomas and parathyroid adenomas.
Concentration 1.8 mg/ml
General Readings 1. Yoshida, S.O. and Imam, A., “Monoclonal antibody to a proximal nephrogenic renal antigen:
immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas.”
Cancer Res. 1989, 49, 1802-1809.
2. Piron, A., et al. “In vitro demonstration of a mitogenic activity in renal tissue extracts during
regenerative hyperplasia.” Am. J. Physiol. 1998, 274, F348-F357
Storage Store the antibody in aliquots at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A chromatography
Buffer System:
PBS, pH 7.2 containing 0.1% Sodium Azide
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody reacts to Renal Cell Carcinoma.
Species:
Human.

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