AM01217PU-N Renal Cell Carcinoma antibody

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Mouse anti Human Renal Cell Carcinoma PN-15


Product Description for Renal Cell Carcinoma

Mouse anti Human Renal Cell Carcinoma PN-15.
Presentation: Purified
Product is tested for Frozen Sections, Western blot / Immunoblot, Paraffin Sections.

Properties for Renal Cell Carcinoma

Product Category Primary Antibodies
Quantity 0.2 mg
Synonyms gp200
Presentation Purified
Reactivity Hu
Applications C, P, WB
Clonality Monoclonal
Clone PN-15
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Renal cortical tissue extract was used to immunize BALB/c mice.
Isotype control AM03110PU-N, SM12P
Application This antibody can be used for the differential diagnosis of carcinomas by Western blotting and
immunohistochemistry on frozen and paraffin-embedded tissues. Protease digestion prior to antibody incubation enhances staining of tissue sections.
Background This antibody reacts with a glycoprotein of 200 kDa present in proximal renal tubules. The antigen is a carbohydrate in nature and retained in formalin fixed paraffin embedded tissues. Other normal tissues that display the antigen include breast, parathyroid glands and epididymis. Among renal carcinomas, 93% of primary and 84% of metastatic carcinomas are positive for this antigen. Relatively few other tumor types are positive: breast cancers, teratocarcinomas and parathyroid adenomas.
Concentration 1.8 mg/ml
General Readings 1. Yoshida, S.O. and Imam, A., “Monoclonal antibody to a proximal nephrogenic renal antigen:
immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas.”
Cancer Res. 1989, 49, 1802-1809.
2. Piron, A., et al. “In vitro demonstration of a mitogenic activity in renal tissue extracts during
regenerative hyperplasia.” Am. J. Physiol. 1998, 274, F348-F357
Storage Store the antibody in aliquots at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein A chromatography
Buffer System:
PBS, pH 7.2 containing 0.1% Sodium Azide
Liquid purified Ig
This antibody reacts to Renal Cell Carcinoma.

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