NB100-64648 Reticulum Cells antibody

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Mouse anti Rat Reticulum Cells ED10


Product Description for Reticulum Cells

Mouse anti Rat Reticulum Cells ED10.
Presentation: Ascites
Product is tested for Frozen Sections, Paraffin Sections.

Properties for Reticulum Cells

Product Category Primary Antibodies
Quantity 0.125 ml
Presentation Ascites
Reactivity Rt
Applications C, P
Clonality Monoclonal
Clone ED10
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rat spleen cell homogenate
Application Immunohistochemistry-Frozen, Immunohistochemistry-Frozen, Immunohistochemistry-Frozen 1:400 - 1:1000
Background Dendritic cells (DCs) are known as the professional antigen presenting cells. DCs perform the important role of capturing and processing antigen and presenting it to naïve T-helper cells to initiate the immune response. Distinct subsets of DCs have been described, they include interdigitating reticulum cells. The antigen recognized by NB100-64648 is found on a subpopulation (approximately 5%) of circulating monocytes and peritoneal macrophages, as well as on in vitro LPS and IFN stimulated macrophages and on all macrophages after 3 weeks in culture. It is absent from all other blood cells. Detects a subpopulation of reticulum cells in T-cell areas of lymph nodes and spleen and their in vitro correlates. It is also useful for the detection of a macrophage subpopulation in the thymus. A minor but distinct population of leukocytes in the kidney cortex is also positively stained by ab15683. The antigen is absent in the skin.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer System:
0.09% Sodium Azide
NB100-64648 recognizes reticular elements in the T cell areas of spleen, lymph nodes, Peyers patches, bronchus and gut associated lymphoid tissues (BALT and GALT). In the thymus a reticular pattern is observed in capsule and medulla (perivascular). Non-lymphoid organs: in liver, lung and small intestine, some ED10 positive reticular are found. No reaction is observed in skin, kidney, brain, pancreas and heart.

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