SM1771P Reticulum Cells antibody

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0.25 mg / €450.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Rat Reticulum Cells ED11


Product Description for Reticulum Cells

Mouse anti Rat Reticulum Cells ED11.
Presentation: Purified
Product is tested for Frozen Sections, Enzyme Immunoassay.

Properties for Reticulum Cells

Product Category Primary Antibodies
Quantity 0.25 mg
Presentation Purified
Reactivity Rt
Applications C, E
Clonality Monoclonal
Clone ED11
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Rat spleen cell homogenate. Spleen cells from immunised BALB/c mice were fused with the mouse SP2/0.Ag14 myeloma cell line.
Application Immunohistochemistry on frozen sections: 1/100 - 1/300. ELISA.
Concentration 0.5 mg/ml
General Readings
  1. Van den Berg TK, Döpp EA, Brevé JJ, Kraal G, Dijkstra CD. The heterogeneity of the reticulum of rat peripheral lymphoid organs identified by monoclonal antibodies. Eur J Immunol. 1989 Sep;19(9):1747-56. PubMed PMID: 2676562.
  2. Van den Berg TK, Döpp EA, Daha MR, Kraal G, Dijkstra CD. Selective inhibition of immune complex trapping by follicular dendritic cells with monoclonal antibodies against rat C3. Eur J Immunol. 1992 Apr;22(4):957-62. PubMed PMID: 1551408.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
PBS containing 0.09% Sodium Azide
Liquid purified IgG
This antibody recognises reticular elements in the T cell areas and B cell follicles of spleen, lymph nodes, Peyers patches, bronchus and gut associated lymphoid tissues (BALT and GALT). In the thymus a reticular pattern is observed throughout the cortex capsule, the medulla is negative. In non-lymphoid organs positivity is seen only in reticular elements of the small intestine. No staining of liver, lung, skin, kidney, brain, pancreas or heart is seen. Biochemical analysis has revealed that ED11 recognises complement factor C3. in vivo studies have shown that ED11 blocks immune complex trapping on follicular dendritic cells.

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