discontinued

GTX80860 RIC Kinase antibody

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0.1 mg / €520.00

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Rabbit anti Human RIC Kinase

GTX80860

Product Description for RIC Kinase

Rabbit anti Human RIC Kinase.
Product is tested for Western blot / Immunoblot.

Properties for RIC Kinase

Product Category Primary Antibodies
Quantity 0.1 mg
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide corresponding to the N-terminal acid residues 11-30 of human RICK.
Application WB
Background Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Cell death signals are transduced by death domain containing adaptor molecules and members of the caspase family of proteases. Certain serine/threonine protein kinases have been implicated to be involved as mediators of apoptosis. The Apo-1 death receptor plays an important role in the homeostasis of the immune system, where it mediates apoptosis. A novel serine/threonine protein kinase, termed RICK (receptor interacting protein-like interacting CLARP (caspase-like apoptosis regulatory protein) kinase), was recently isolated which regulates Apo-1 mediated apoptosis. RICK contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal domain that is involved in the binding of caspases. Overexpression of RICK promotes caspase-8 activation and Fas ligand-mediated apoptosis.
Storage -20
Format
State:
100 ug (0.5 mg/ml) purified rabbit IgG in PBS containing 0.02% sodium azide.
Specificity
Specificity:
Human

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