discontinued

GTX10202 S100 antibody

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0.1 mg / €290.00

Quick Overview

Mouse anti Human S100 4E3

GTX10202

Product Description for S100

Mouse anti Human S100 4E3.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot, Paraffin Sections.

Properties for S100

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Astrocyte Marker, S-100 protein, S-100 protein alpha subunit, S-100 protein beta subunit, S100 Alpha, S100 Beta, S100 Calcium binding protein
Presentation Purified
Reactivity Hu
Applications E, P, WB
Clonality Monoclonal
Clone 4E3
Host Mouse
Isotype IgG2a
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Human S-100 protein
Isotype control AM03096PU-N
Application IA, P, WB
Background S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.
Format
Purification:
Protein A purified
Buffer System:
Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4
Purity:
Protein A purified
State:
Purified
Specificity
Specificity:
Human - Not yet tested in other species

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