GTX72530 S100 antibody

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1 ml / €260.00

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Mouse anti Bovine, Chicken, Human, Mouse, Rat S100 B32.1


Product Description for S100

Mouse anti Bovine, Chicken, Human, Mouse, Rat S100 B32.1.
Presentation: HRP
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections.

Properties for S100

Product Category Primary Antibodies
Quantity 1 ml
Synonyms Astrocyte Marker, S-100 protein, S-100 protein alpha subunit, S-100 protein beta subunit, S100 Alpha, S100 Beta, S100 Calcium binding protein
Presentation HRP
Reactivity Bov, Chk, Hu, Ms, Rt
Applications ICC/IF, P
Clonality Monoclonal
Clone B32.1
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Purified Bovine S-100 Protein
Application IF, IHC-P
Background S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.
Concentration 0.1 mg/ml
Storage Keep as concentrated solution, aliquot and store at 4
Buffer System:
50 mM potassium phosphate, 150 mM sodium chloride, bovine serum albumin, carrier polysaccharides, and 0.1% sodium azide, pH 7.2.
Human, Mouse, Rat, Porcine, Bovine, Cat, Chicken, and Baboon - Not yet tested in other species

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