NB100-56692 SARS Nucleocapsid Protein antibody

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Mouse anti Human SARS Nucleocapsid Protein 18F629.1


Product Description for SARS Nucleocapsid Protein

Mouse anti Human SARS Nucleocapsid Protein 18F629.1.
Presentation: Ascites
Product is tested for Western blot / Immunoblot.

Properties for SARS Nucleocapsid Protein

Product Category Primary Antibodies
Quantity 0.2 ml
Presentation Ascites
Reactivity Hu
Applications WB
Clonality Monoclonal
Clone 18F629.1
Host Mouse
Isotype IgM
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

The antibody was developed by immunizing mice with a KLH-conjugated peptide corresponding to amino acids 354-370 of human nucleocapsid protein (Genbank accession no. NP_828858).
Background It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
Buffer System:
PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic.
Human Not yet tested in other species.

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