GTX23432 SCAMP5 antibody

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0.1 mg / €380.00

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Rabbit anti Mouse, Rat SCAMP5

Product Description for SCAMP5

Rabbit anti Mouse, Rat SCAMP5.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for SCAMP5

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic Peptide: CN(217)QPQTQYSATPNYTYSN(233).Immunizing peptide corresponds to amino acid residues 217-233 from rat SCAMP 5. This sequence is 94% conserved in mouse.
Application WB
Background Secretory Carrier Membrane Proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.
Concentration 1 mg/ml
Storage Upon receipt - Keep as concentrated solution. Aliquot and store at -20
Immunogen affinity purified
Buffer System:
PBS, 1 mg/ml BSA and 0.05% sodium azide
Immunogen affinity purified
Aff - Purified
Cross-reacts with Rat. Expected to cross-react with Mouse due to sequence homology. Not yet tested in other species.

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