TA336640 SCARB2 antibody

Rabbit Polyclonal LIMPII/SR-B2 Antibody

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0.1 ml / €451.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Bovine, Human, Mouse, Rat SCARB2

TA336640

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  • TA336640

Product Description for SCARB2

Rabbit anti Bovine, Human, Mouse, Rat SCARB2.
Presentation: Purified
Product is tested for Frozen Sections, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for SCARB2

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms 85 kDa lysosomal membrane sialoglycoprotein, CD36 antigen-like 2, CD36L2, LGP85, LIMP II, LIMP2, LIMPII, Lysosome membrane protein 2, SR-BII, SRB2, Scavenger receptor class B member 2
Presentation Purified
Reactivity Bov, Hu, Ms, Rt
Applications C, F, ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q14108
Immunogen:
A peptide containing residues from mouse SR-BII (between residues 400-478) plus an N-terminal cysteine was coupled to KLH. [UniProt# O35114].
GeneID:
950
Application WB: 1:1000
FC:
IF: 1:25-1:100
IHC: 1:25
IHC-P: 1:25
Background Scavenger receptor class BI or SCARB1 gene belongs to CD36 receptor family and encodes for at least two mR splice variants which are SR-BI and SR-BII, among which SR-BII variant is the main isoform in terms of mR levels in certain tissues. For example, SR-BII mR is 48-fold higher than SR-BI in brain cells and protein levels reaching 10-15% of SR-BI in the liver. Similar differential SR-BII protein expression levels have also been detected in considerable amounts in other tissues, such as testes, retil pigment epithelial cells, and spleen. SR-BII isoform differs from SR-BI only in its entirely different, yet highly conserved, cytoplasmic C-terminus which has been proposed to contains a sigl responsible for marked alterations in cellular distribution as well as cellular trafficking of SR-BII compared with SR-BI. In contrast to SR-BI, SR-BII mediates the rapid uptake of significant amounts of HDL into endosomal recycling compartment by a pathway which is different from selective lipid uptake at the cell surface (mediated by SR-BI). Because SR-BII influence cellular cholesterol trafficking/homeostasis in a manner distinct from SR-BI, the relative expression as well as functiol activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
Format
Purification:
Whole antisera
Buffer System:
Tris-citrate/phosphate, pH 7, 0.09% Sodium azide. Store at 4C. Do not freeze.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for SCARB2 (6 products)

Catalog No. Species Pres. Purity   Source  

SCARB2

SCARB2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

SCARB2

SCARB2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

SCARB2

SCARB2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

SCARB2

SCARB2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

SCARB2

SCARB2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

SCARB2

SCARB2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for SCARB2 (1 products)

Catalog No. Species Pres. Purity   Source  

SCARB2 293T Cell Transient Overexpression Lysate(Denatured)

SCARB2 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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