GTX30630 Scavenger Receptor BI/II antibody

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0.1 ml / €480.00

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Rabbit anti Human, Mouse, Rat Scavenger Receptor BI/II


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  • GTX30630
  • GTX30630
  • GTX30630

Product Description for Scavenger Receptor BI/II

Rabbit anti Human, Mouse, Rat Scavenger Receptor BI/II.
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.

Properties for Scavenger Receptor BI/II

Product Category Primary Antibodies
Quantity 0.1 ml
Reactivity Hu, Ms, Rt
Applications C, ICC/IF, IP, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

A peptide from the extracellular domain (residues 230-380) of Scavenger Receptor-BI/BII was expressed as two tandem copies in bacteria using the pET system.
Application IF, IHC, IP, WB
Background High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues.Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
Concentration antiserum
Storage Store at -20?C. Avoid repeated freeze-thaw cycles.
Whole antisera
Whole antisera
0.1 ml of whole rabbit sera with 0.02% sodium azide.
Reacts with mouse. Previous lots have been shown to react with rat and human Scavenger Receptors-BI and -BII, as well.

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