discontinued

GTX23660 SENP2 antibody

See related secondary antibodies

Search for all "SENP2"

0.1 mg / €410.00

Quick Overview

Rabbit anti Human, Mouse, Rat SENP2

GTX23660

More Views

  • GTX23660

Product Description for SENP2

Rabbit anti Human, Mouse, Rat SENP2.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for SENP2

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu, Ms, Rt
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide: KTKRNSDLNLLEWTHHS, corresponding to amino acids 517-533 of Human SENP 2.
Application ELISA, WB
Background Covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respects to size and ubiquity - to which eukaryotic proteins are subject. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied for over two decades. Recently a new group of ubiquitin-like (Ubl) proteins have come to light. One of the most intriguing of them is SUMO (small ubiquitin-like modifier, ~12kDa) also known as Sentrin. SUMO family has been described in vertebrates: SUMO-1 and the closest homologs SUMO-2 and SUMO-3. SUMO have been shown to bind and regulate mammalian SP-RINGs (such as Mdm2, PIAS and PML), RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, Drosophila Ttk69, Dorsal, CaMK, yeast Septins, and viral CMV-IE1/2, EBV-BZLF1, HPV/BPV-E1. These bindings implicate SUMO in the stabilization of the target proteins and/or their localization to subcellular complexes. SUMO research enters now an exciting phase with a promise to help understanding how cells orchestrate the complexities of rapidly regulating protein level and activity.
Concentration 0.25 mg/ml
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Protein G purified
Buffer System:
PBS with 0.1% sodium azide
Purity:
Protein G purified
State:
Liquid
Purified
Specificity
Specificity:
Cross-reacts with Human. Expected to cross-react with Mouse (88% identical),Rat (88% identical) due to sequence homology. Not yet tested in other species.

Accessory Products

  • LinkedIn