NB100-74532 Serotonin N-AT Phosphospecific antibody

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Rabbit anti Rat Serotonin N-AT Phosphospecific


Product Description for Serotonin N-AT Phosphospecific

Rabbit anti Rat Serotonin N-AT Phosphospecific.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Serotonin N-AT Phosphospecific

Product Category Primary Antibodies
Quantity 0.05 mg
Presentation Aff - Purified
Reactivity Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Synthetic Peptide: C(a.a. 24) Q R R H T(p) L P A S(a.a. 33)
Application Western Blot 0.5 µg/ml
Background Pineal gland serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT) is an ~23 kDa protein which is the rate-limiting enzyme in melatonin synthesis. Melatonin serves as the hormonal signal of the daily light/dark cycle, or body clock. The nocturnal oscillation in enzyme activity ranges by 10- to 100-fold depending on species among vertebrates. Studies have shown that AA-NAT is regulated by cAMP at both the mRNA and protein levels. AA-NAT has putative protein kinase A (PKA) sites at Thr29 and Ser206. Phosphorylation of AA-NAT at these residues might play a role in protein inactivation via proteasome-dependent degradation.
Concentration 1 mg/ml
Storage Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Immunogen affinity purified
Aff - Purified
This antibody is reactive against Rat.

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