TA302602 Serotonin receptor 3A (HTR3A) antibody

Goat Polyclonal Antibody against Serotonin receptor 3A / HTR3A

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0.1 mg / €360.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Goat anti Human, Rat Serotonin receptor 3A (HTR3A)

Product Description for Serotonin receptor 3A (HTR3A)

Goat anti Human, Rat Serotonin receptor 3A (HTR3A).
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Serotonin receptor 3A (HTR3A)

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, Serotonin-gated ion channel receptor
Presentation Aff - Purified
Reactivity Hu, Rt
Applications E, ICC/IF, WB
Clonality Polyclonal
Host Goat
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Swiss Prot Num:
Peptide with sequence from the internal region of the protein sequence according to NP_998786.2; NP_000860.2; NP_001155244.1.
AA Sequence:
Application Peptide ELISA: 1/128000 (Detection Limit).
Western Blot: 0.3-1 µg/ml. Detects a band of ~55kDa in Human Colon lysates (Calculated MW of 55.3kDa according to NP_000860.1). An additional band of unknown identity was also consistently observed at 200kDa. This band was successfully blocked by incubation with the immunising peptide. 
Immunocytochemistry/Immunofluorescence: This antibody has been successfully used in ICC/IF for Rat neurons as described by Lu et al in Reference 1.
Background 5-hydroxytryptamine (serotonin) receptors is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The 5HT3A receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Concentration 0.5 mg/ml
Product Citations
Purchased from Acris:
  1. Silva M, Martins D, Tavares I, Morgado C. Inhibition of spinal 5-HT3R reverted diabetes-induced mechanical hypersensitivity in a GABAAR-mediated neurotransmission-dependent manner. Neuroscience. 2015 Sep 24;304:228-39. doi: 10.1016/j.neuroscience.2015.07.050. Epub 2015 Jul 23. PubMed PMID: 26210577.
Originator or purchased from resellers:
  1. Lu CL, Hsieh JC, Dun NJ, Oprea TI, Wang PS, Luo JC, et al. Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats. Gastroenterology. 2009 Sep;137(3):1040-50. doi: 10.1053/j.gastro.2009.03.047. Epub 2009 Apr 1. PubMed PMID: 19344720.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Buffer System:
Tris saline, pH~7.3
0.02% Sodium Azide
0.5% BSA
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Rat.
This antibody is expected to recognize all three reported isoforms (NP_998786.2; NP_000860.2; NP_001155244.1).

Accessory Products

Proteins and/or Positive Controls

Proteins for Serotonin receptor 3A (HTR3A) (1 products)

Catalog No. Species Pres. Purity   Source  

Serotonin receptor 3A (HTR3A)

Serotonin receptor 3A (HTR3A) Human
  Abnova Taiwan Corp.

Positive controls for Serotonin receptor 3A (HTR3A) (2 products)

Catalog No. Species Pres. Purity   Source  

5HT3A receptor Lysate

Western Blot: 5HT3A receptor Lysate [NBL1-11779] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for HTR3A
  Novus Biologicals Inc.

HTR3A overexpression lysate

HTR3A overexpression lysate
0.1 mg / €315.00
  OriGene Technologies, Inc.
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