DM1004 Serum Amyloid A protein (SAA) antibody

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0.5 mg / €580.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Serum Amyloid A protein (SAA) 607

DM1004

Product Description for Serum Amyloid A protein (SAA)

Mouse anti Human Serum Amyloid A protein (SAA) 607.
Presentation: Purified
Product is tested for ELISA (detection), Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Serum Amyloid A protein (SAA)

Product Category Primary Antibodies
Target Category
Quantity 0.5 mg
Synonyms SAA1, SAA2
Presentation Purified
Reactivity Hu
Applications E, E(detection), WB
Clonality Monoclonal
Clone 607
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P02735
Immunogen:
Highly Purified recombinant Human SAA (MW: 12kDa)
GeneID:
6288
Isotype control AM03096PU-N
Application ELISA: Matched Pair: Clone 607 (Cat.-No DM1004) / Clone 115 (Cat.-No DM1002). 
Western Blot: 0.1-0.5 µg will allow visualization of 100 ng/lane of recombinant human SAA.
Background The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP.
SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.
General Readings
  1. Wu TL et al. Establishment of an in-house ELISA and the reference range for serum amyloid A (SAA): complementarity between SAA and C-reactive protein as markers of inflammation. 2007 Feb; Clin Chim Acta. 376(1-2):72-6.
  2. Yeop Han C, Kargi AY, Omer M, Chan CK, Wabitsch M, O'Brien KD, et al. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. Diabetes. 2010 Feb;59(2):386-96. doi: 10.2337/db09-0925. Epub 2009 Nov 23. PubMed PMID: 19934003. (Free PMC Article available, 8 images available)
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography on Protein G
Buffer System:
0.01M PBS, pH 7.2
State:
Lyophilized purified IgG fraction
Purified
Reconstitution:
Restore with Double distillated water is recommended, adjust the final concentration to 1.0 mg/ml
Specificity
Specificity:
Reacts with natural and recombinant Human SAA.
Does not show any cross-reaction with other Human cytokines or growth factors tested such as IL-1β, IL-8, MCAF, TGF-β and EGF.
Species:
Human.
Gene ID 6289

Accessory Products

Proteins and/or Positive Controls

Proteins for Serum Amyloid A protein (SAA) (15 products)

Catalog No. Species Pres. Purity   Source  

Serum Amyloid A protein (SAA) (19-122, His-tag)

Recombinant human Serum amyloid A, 19-122 aa, His-tagged Human Purified > 95 % pure by SDS-PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

Serum Amyloid A protein (SAA) (19-122, His-tag)

Recombinant human Serum amyloid A, 19-122 aa, His-tagged Human Purified > 95 % pure by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

Serum Amyloid A protein (SAA) (Apo-SAA1)

Serum Amyloid A protein (SAA) Human > 98 % pure by SDS-PAGE and HPLC analyses E. coli
  Acris Antibodies GmbH

Serum Amyloid A protein (SAA) (Apo-SAA1)

Serum Amyloid A protein (SAA) Human > 98 % pure by SDS-PAGE and HPLC analyses E. coli
  Acris Antibodies GmbH

Serum Amyloid A protein (SAA)

Serum Amyloid A protein (SAA) Human > 98 % Greater than 98% by SDS-PAGE gel and HPLC analyses E. coli
  Acris Antibodies GmbH

Serum Amyloid A protein (SAA) (SAA1)

Serum Amyloid A protein (SAA) Human in vitro transl.
  Abnova Taiwan Corp.

Serum Amyloid A protein (SAA) (SAA1)

Serum Amyloid A protein (SAA) Human in vitro transl.
  Abnova Taiwan Corp.

Serum Amyloid A protein (SAA)

Serum Amyloid A protein (SAA) Human
  Abnova Taiwan Corp.

Serum Amyloid A protein (SAA)

Serum Amyloid A protein (SAA) Human
  Abnova Taiwan Corp.

Serum Amyloid A protein (SAA) (SAA2)

Serum Amyloid A protein (SAA) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Serum Amyloid A protein (SAA) (SAA2)

Serum Amyloid A protein (SAA) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Serum Amyloid A protein (SAA)

Serum Amyloid A protein (SAA) Human
  Abnova Taiwan Corp.

Serum Amyloid A protein (SAA)

Serum Amyloid A protein (SAA) Human > 96 % Serum
  BBI Solutions

Serum Amyloid A protein (SAA)

SDS-Page: Serum Amyloid A Protein [NBP1-30209] - Serum amyloid A, 13.9 kDa (125aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE Human Purified
  Novus Biologicals Inc.

Serum Amyloid A protein (SAA)

Serum Amyloid A protein (SAA) Human Purified
  Novus Biologicals Inc.

Positive controls for Serum Amyloid A protein (SAA) (3 products)

Catalog No. Species Pres. Purity   Source  

SAA2 Lysate (SAA2)

Western Blot: SAA2 Lysate [NBL1-15672] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for SAA2
  Novus Biologicals Inc.

Serum Amyloid A Lysate

Western Blot: Serum Amyloid A Lysate [NBL1-15670] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for SAA1
  Novus Biologicals Inc.

Serum Amyloid A Lysate

Western Blot: Serum Amyloid A Lysate [NBL1-15671] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for SAA1
  Novus Biologicals Inc.
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