Product Description for SHANK3
Rabbit anti Human, Mouse SHANK3.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Immunocytochemistry/Immunofluorescence, Enzyme Immunoassay, Western blot / Immunoblot.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Immunocytochemistry/Immunofluorescence, Enzyme Immunoassay, Western blot / Immunoblot.
Properties for SHANK3
Product Category | Primary Antibodies |
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Quantity | 0.1 mg |
Synonyms | PSAP2, ProSAP2, Proline-rich synapse-associated protein 2, SH3 and multiple ankyrin repeat domains 3, SPANK-2 |
Presentation | Aff - Purified |
Reactivity | Hu, Ms |
Applications | E, ICC/IF, P, WB |
Clonality | Polyclonal |
Host | Rabbit |
Isotype | IgG |
Shipping to | Europe, USA/Canada |
PDF datasheet | View Datasheet |
Manufacturer | OriGene Technologies, Inc. |
Datasheet Extract
Immunogen |
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Property | Center |
Add. information | Blocking peptide available: AP55426CP-N |
Application | Western blot: 1-2 µg/ml. Positive Control: 3T3 cell lysate. Immunofluorescence: Start at 2.5 μg/ml. Immunohistochemistry on Paraffin Sections: Start at 2.5 µg/ml. |
Background | SH3 and multiple ankyrin repeat domains 3 (SHANK3), a member of the Shank gene family, plays a role in synapse formation and dendritic spine maturation. Shank proteins (Shank 1-3) containing PDZ domains are scaffold proteins of the postsynaptic density (PSD) that connect neurotransmitter receptors and ion channels proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development. Mutations of SHANK3 are a cause of autism spectrum disorder (ASD) and the neurological symptoms of 22q13.3 deletion syndrome. |
Concentration | 1.0 mg/ml |
General Readings |
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Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Format |
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Species Reactivity |
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Specificity |
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Accessory Products
Recommended Secondary Antibodies for SHANK3 (9 products)
Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
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R1364AP |
Rabbit IgG (H+L chain) antibody |
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Goat | AP | Rb | E, WB | |||
Acris Antibodies GmbH | |||||||
R1364B |
Rabbit IgG (H+L chain) antibody |
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Goat | Biotin | Rb | E, WB | |||
Acris Antibodies GmbH | |||||||
R1364F |
Rabbit IgG (H+L chain) antibody |
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Goat | FITC | Rb | E, ICC/IF, WB | |||
Acris Antibodies GmbH | |||||||
R1364HRP |
Rabbit IgG (H+L chain) antibody |
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Goat | HRP | Rb | E, P, WB | |||
Acris Antibodies GmbH | |||||||
R1364T |
Rabbit IgG (H+L chain) antibody |
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Goat | TRITC | Rb | E, F, ICC/IF | |||
Acris Antibodies GmbH | |||||||
R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
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Donkey | PE | Rb | F | |||
Acris Antibodies GmbH | |||||||
R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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Goat | Cy2 | |||||
Acris Antibodies GmbH | |||||||
R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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Goat | Cy3 | |||||
Acris Antibodies GmbH | |||||||
R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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Goat | Cy5 | |||||
Acris Antibodies GmbH |