discontinued

bs-3398R SHIP1 pTyr1020 antibody

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0.1 ml / €250.00

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Rabbit anti Human, Mouse, Rat SHIP1

bs-3398R

Product Description for SHIP1

Rabbit anti Human, Mouse, Rat SHIP1.
Properties: pTyr1020
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for SHIP1

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms 4, 5 trisphosphate 5 phosphatase 1, 5-trisphosphate 5-phosphatase 1, INPP 5D, INPP5D, INPP5D protein, Inositol polyphosphate 5 phosphatase, Inositol polyphosphate 5 phosphatase 145kDa, Inositol polyphosphate 5 phosphatase D, Inositol polyphosphate 5 phosphatase of 145kDa, Inositol polyphosphate-5-phosphatase of 145 kDa, MGC104855, MGC142140, MGC142142, P-SHIP1 Tyr1020, Phosphatidylinositol 3, Phosphatidylinositol-3, SH2 containing inositol 5 phosphatase, SH2 containing inositol phosphatase isoform b, SH2 domain containing inositol 5' phosphatase 1, SH2 domain containing inositol phosphatase 1, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol-5''-phosphatase 1, SHIP 1, SHIP-1, SHIP1, SHIP1_RAT, SIP 145, SIP-145, SIP145., Signaling inositol polyphosphate 5 phosphatase SIP 145, Signaling inositol polyphosphate 5 phosphatase SIP145, hSHIP, hp51CN, p150 ship, p150Ship
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
O00145
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human SHIP1 around the phosphorylation site of Tyr1020.
GeneID:
3635
Property pTyr1020
Application WB(1:100-1000)
IHC-P(1:100-500)
IF(IHC-P)(1:50-200)
Background SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Storage Store at -20°C for 12 months.
Format
Purification:
Purified by Protein A.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
State:
Purified

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