NSB557 SHP2 antibody

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Rabbit anti Human SHP2

Product Description for SHP2

Rabbit anti Human SHP2.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for SHP2

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human SHP2 that contains serine 576. The sequence is conserved in mouse, rat and chicken.
Add. information Research Areas: Cancer
Application Western Blot, This antibody is suitable for use in Western blotting. The recommended concentration for use in Western blotting is 1:1,000. *The optimal concentration should be determined for each specific application. , Western Blot
Background SHP2 (SH2-domain containing tyrosine phosphatase 2, also known as SHPTP2) is a ~70 kDa tyrosine phosphatase that plays an important role in cell growth and transformation and in mediating integrin, Src and receptor tyrosine kinase (RTK) signaling. SHP2 undergoes tyrosine phosphorylation on several sites including tyrosines 542 and 580 upon binding to platelet-derived growth factor receptor beta (PDGFRb), in response to PDGF stimulation. Serines 576 and 591 are phosphorylated by protein kinase C isoforms alpha, beta 1, beta 2, and eta, and in response to phorbol ester.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
0.05% Sodium Azide
Immunogen affinity purified
Aff - Purified
SHP2 [Ser576]

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