NB100-876 SIAH Interacting Protein antibody

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0.1 mg / €250.00

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Goat anti Human SIAH Interacting Protein


Product Description for SIAH Interacting Protein

Goat anti Human SIAH Interacting Protein.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for SIAH Interacting Protein

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Goat
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Synthetic peptide with sequence VESREKQAKGDTEF representing the C-Terminus of the human protein (residues 215-228) according to NP_055227.
Background **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognize native protein in any application.

The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Concentration 0.5 mg/ml
General Readings Matsuzawa SI & Reed JC Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses. Mol Cell 7:915-26 (2001). PubMed PMID: 11389839
Immunogen affinity purified
Buffer System:
Tris saline containing [pH7.3] with 0.5% BSA
Immunogen affinity purified
Aff - Purified
Expected to cross-react with Human due to sequence homology. Not yet tested in other species.

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