discontinued

GTX19388 SIRT2 antibody

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0.1 ml / €440.00

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Rabbit anti Human, Rat SIRT2

GTX19388

Product Description for SIRT2

Rabbit anti Human, Rat SIRT2.
Presentation: Serum
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for SIRT2

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Serum
Reactivity Hu, Rt
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide: LEDLVRREHA SI, corresponding to amino acids 341-352 of Human SIRT2.
Application ICC, WB
Background The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise.SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Whole antiserum
Buffer System:
Preservative: 0.05% Sodium Azide
Purity:
Whole antiserum
State:
Serum
Specificity
Specificity:
Cross-reacts with Human and Rat. Not yet tested in other species.

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