discontinued

GTX13682 SIRT7 antibody

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0.1 mg / €440.00

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Rabbit anti Human, Mouse, Rat SIRT7

GTX13682

Product Description for SIRT7

Rabbit anti Human, Mouse, Rat SIRT7.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for SIRT7

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptides: ILRKAAAERSAEEGRLL & CRSREEAPPGDRGAPLS corresponding to amino acids 35-51 & 361-377 of Human SIRT7.
Application WB
Background SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolise NAD and possibly act as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Concentration 0.5 mg/ml
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Protein G purified
Buffer System:
Preservative: 0.02% Sodium Azide; Constituents: PBS, 1mg/ml BSA
Purity:
Protein G purified
State:
Purified
Specificity
Specificity:
Expected to cross-react with Mouse (100% identity with immunogen), Human (100% identity with immunogen) and Rat (88% identity with immunogen) due to sequence homology. Not yet tested in other species.

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