AM05887FC-N SLA CLASS II DR antibody

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0.1 mg / €550.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Bovine, Porcine SLA CLASS II DR 2E9/13


Product Description for SLA CLASS II DR

Mouse anti Bovine, Porcine SLA CLASS II DR 2E9/13.
Presentation: FITC
Product is tested for Functional assay, Flow Cytometry.

Properties for SLA CLASS II DR

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms MHC Class II DR
Presentation FITC
Reactivity Bov, Por
Applications F, FN
Clonality Monoclonal
Clone 2E9/13
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Porcine monocytes.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63-Ag.8.653 myeloma cell line.
Isotype control SM12F
Application Flow Cytometry: Use 10 µl of neat antibody to label 1x10e6 cells in 100 µl.
Functional Assays: Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B (Ref.1).
Concentration 0.1 mg/ml
General Readings
  1. Bullido R, Doménech N, Alvarez B, Alonso F, Babín M, Ezquerra A, et al. Characterization of five monoclonal antibodies specific for swine class II major histocompatibility antigens and crossreactivity studies with leukocytes of domestic animals. Dev Comp Immunol. 1997 May-Jun;21(3):311-22. PubMed PMID: 9258612.
  2. Jeong HJ, Song YJ, Lee SW, Lee JB, Park SY, Song CS, et al. Comparative measurement of cell-mediated immune responses of swine to the M and N proteins of porcine reproductive and respiratory syndrome virus. Clin Vaccine Immunol. 2010 Apr;17(4):503-12. doi: 10.1128/CVI.00365-09. Epub 2010 Feb 3. PubMed PMID: 20130128. (Free PMC Article available, 8 images available)
  3. Ding Q, Lu L, Zhou X, Zhou Y, Chou KY. Human PD-L1-overexpressing porcine vascular endothelial cells induce functionally suppressive human CD4+CD25hiFoxp3+ Treg cells. J Leukoc Biol. 2011 Jul;90(1):77-86. doi: 10.1189/jlb.1210691. Epub 2011 Apr 15. PubMed PMID: 21498584.
Storage Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Fluorescein Isothiocyanate Isomer 1
Affinity Chromatography on Protein G.
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Liquid purified Ig fraction.
This antibody is specific for Porcine MHC Class II DR molecules (SLA-II DR). Porcine SLA-II molecules are expressed on all B cells, on antigen presenting cells and on certain subsets of resting and activated T cells.
This clone reacts with lymphocytes from all outbred and miniature Pigs so far tested, suggesting that it recognises a monomorphic determinant of Porcine SLA-II DR.
This antibody immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled porcine peripheral blood mononuclear cells.
Pig. Cross reacts with Bovine.

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