discontinued

GTX29262 SMC1 antibody

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50 µg / €340.00

Quick Overview

Rabbit anti Human, Mouse, Rat, Xenopus SMC1

GTX29262

Product Description for SMC1

Rabbit anti Human, Mouse, Rat, Xenopus SMC1.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.

Properties for SMC1

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt, Xen
Applications ICC/IF, IP, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide (Human) conjugated to KLH - which represents a portion within the last 100 amino acids of the human Structural Maintenance of Chromosomes-1 (GenBank PID 5453642).
Application ICC, IF, IP, WB
Background Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, and works as a downstream effector in the ATM/NBS1 branch of S-phase checkpoint.
Concentration 1 mg/ml
Storage Keep as concentrated solution, aliquot and store at 4
Format
Purification:
Immunogen affinity purified
Buffer System:
Tris-citrate/phosphate, pH 7-8, 0.1% sodium azide
Purity:
Immunogen affinity purified
State:
Liquid
Aff - Purified
Specificity
Specificity:
Cross-reacts with Human and Xenopus . Expected to cross-react with Mouse, Rat and Cow due to sequence homology. Not yet tested in other species.

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