GTX21275 SMC1 (phospho S957) antibody

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50 µg / €370.00

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Rabbit anti Human SMC1 (phospho S957)


Product Description for SMC1 (phospho S957)

Rabbit anti Human SMC1 (phospho S957).
Presentation: Aff - Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot.

Properties for SMC1 (phospho S957)

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Hu
Applications IP, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic phospho peptide conjugated to KLH (LocusLink ID 8243).
Application IP, WB
Background Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, and works as a downstream effector in the ATM/NBS1 branch of S-phase checkpoint.
Concentration 1 mg/ml
Storage Keep as concentrated solution. Store at 4
Immunogen affinity purified
Buffer System:
Tris-citrate/phosphate, pH 7-8, 0.1% sodium azide
Immunogen affinity purified
Aff - Purified
Human - Not yet tested in other species

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