NB100-2372 SMC3 antibody

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Rabbit anti Human, Mouse SMC3

Product Description for SMC3

Rabbit anti Human, Mouse SMC3.
Presentation: Aff - Purified
Product is tested for Frozen Sections.

Properties for SMC3

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Aff - Purified
Reactivity Hu, Ms
Applications C
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

The epitope recognized by NB 100-2372 maps to a region surrounding residue 1083 when Serine 1083 is phosphorylated of human Structural Maintenance of Chromosomes 3 using the numbering given in SwissProt entry Q9UQE7 (GeneID 9126).
Background This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
Affinity purified
Buffer System:
Tris-buffered Saline containing 0.1% BSA
Affinity purified
Aff - Purified
Human and mouse. Other species have not been tested.

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