GTX80846 Smoothelin antibody

See related secondary antibodies

Search for all "Smoothelin"

0.1 mg / €520.00

Quick Overview

Mouse anti Canine, Chicken, Feline, Human Smoothelin R4A


Product Description for Smoothelin

Mouse anti Canine, Chicken, Feline, Human Smoothelin R4A.
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Smoothelin

Product Category Primary Antibodies
Quantity 0.1 mg
Reactivity Can, Chk, Fe, Hu
Applications C, ICC/IF, WB
Clonality Monoclonal
Clone R4A
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Cytoskeletal smoothelin extract of chicken gizzard.
Application IF, IHC, WB
Background Smoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC-like characteristics, such as myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle do not contain smoothelin. Confocal scanning laser microscopy of tissue sections, as well as transfection studies, show a filamentous organization of smoothelin that is different from that of desmin and vimentin. Smoothelin colocalizes with actin stress fibers. Two tissue specific isoforms have been identified: a 59 kDa isoform specific for visceral SMC; and a 100 kDa specific for vascular SMC. Human smoothelin is encoded by a single copy gene which is located on chromosome 22.
Storage -20
100 ug of epitope affinity purified antibody (0.5 mg/ml) in PBS containing 0.1% sodium azide.
Canine, Chicken, Feline, Human, Non-human primate

Accessory Products

  • LinkedIn