discontinued

AP22235PU-N SOX (pan) antibody

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0.1 mg / €340.00

Quick Overview

Rabbit anti Canine, Human, Monkey, Mouse, Opossum, Rat, Xenopus SOX

Product Description for SOX

Rabbit anti Canine, Human, Monkey, Mouse, Opossum, Rat, Xenopus SOX.
Properties: (pan)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for SOX

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Can, Hu, Mky, Ms, Op, Rt, Xen
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Amino acids 196-213 of human SOX3
AA Sequence:
AVHMKEYPDYKYRPRRK
Remarks:
The amino acid sequence used as immunogen shares significant homology with SOX1, 2, 3, 7, 11, 12, 14, 15, 20, and 21.
Property pan
Application Western blot.
Background SOX3 is a SOX (SRY-related HMG-box) protein that shows its homology with SRY, the testis-determining gene. The homology is restricted to the region of SRY that encodes a DNA-binding motif of the HMG-box class (the DNA-binding domain is called HMG for 'high mobility group'). The SOX gene is located on the X chromosome. This gene is highly conserverd and shows 97.2% similarity to the protein encoded by the mouse SOX3 gene. Along with SOX1 and SOX2, SOX3 coexpresses in self-renewing progenitor cells and act to inhibit neuronal differentiation. Active repression of the SOX genes promotes neural progenitor cells to initiate differentiation prematurely. It helps in pituitary development.
Concentration 0.5 mg/ml
General Readings
  1. Stevanovic, M. et al. Hum. Molec. Genet. 2:2013-2018 (1993).
  2. Bylund, M. et al. Nature Neurosci. 6:1162-1168 (2003).
  3. Weiss, J. et al. Molec. Cell. Biol. 23:8084-8091 (2003).
  4. Rizzoti, K. et al. Nature Genet. 36:247-255 (2004).
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Antigen affinity chromatography
Buffer System:
PBS containing 0.05% BSA and 0.05% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Zebrafish
Species reactivity (tested):
Dog, Human, New World monkey, Mouse, Opossum, Rat, Xenopus
Specificity
Specificity:
This antibody detects SOX.

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