DM3202 SREBP1 antibody

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Mouse anti Hamster, Human SREBP1 2A4


Product Description for SREBP1

Mouse anti Hamster, Human SREBP1 2A4.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for SREBP1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms SREBP-1
Presentation Purified
Reactivity Hst, Hu
Applications WB
Clonality Monoclonal
Clone 2A4
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Biomeda

Datasheet Extract

Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1.
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application Immunoprecipitation. Western Blot (1-2 µg/ml for 2 hrs at RT). Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
General Readings
  1. Wang, X., et al. J. Biol. Chem. 270:15044-18050.
  2. Wan
Storage Store the antibody at 4-8°C. Do not freeze. Shelf life: one year from despatch.
Human SREBP-1 (Epitope: aa 301-407). SREBP-1 and -2 are transcription factors which participate in the control of cholesterol homeostasis. SREBPs proteins, which are attached to the endoplasmic reticulum and nuclear envelope, are proteolytically cleaved and thus activated in response to conditions of low cellular sterol. Recommended positive control: HeLa and IMR5 cells. Cellular Localization: Cytoplasmic, Nuclear. Species Reactivity: Human and Hamster. Others not tested.

Mol. Wt. of Antigen: 125kD (precursor) and 60-70kD (cleaved).

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