GTX30311 Structural Maintenance of Chromosomes-3 (SMC3) antibody

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0.1 mg / €410.00

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Rabbit anti Bovine, Mouse, Xenopus Structural Maintenance of Chromosomes-3 (SMC3)


Product Description for Structural Maintenance of Chromosomes-3 (SMC3)

Rabbit anti Bovine, Mouse, Xenopus Structural Maintenance of Chromosomes-3 (SMC3).
Product is tested for Frozen Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for Structural Maintenance of Chromosomes-3 (SMC3)

Product Category Primary Antibodies
Quantity 0.1 mg
Reactivity Bov, Ms, Xen
Applications C, IP, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Rabbits were immunized with a synthetic peptide, which represented a portion of human Structural Maintenance of Chromosomes-3 encoded within exon 28 (LocusLink ID 9126). Antibodies were affinity purified using the peptide immobilized on solid support.
Application IHC, IP, WB
Background Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis and in chromosome movement.
Storage Keep as concentrated solution, aliquot and store at 4
This antibody reacts with Homo sapiens. Other species have not been tested. Mouse and Bovine expected based upon sequence identity. Mismatches: Xenopus laevis

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