AP05150PU-N SURF1 antibody

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0.1 mg / €360.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human SURF1

Product Description for SURF1

Rabbit anti Human SURF1.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for SURF1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Ssu72
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Full length recombinant human Ssu72 protein
Application Western Blot: 1 - 5 µg/ml.
Background Human Ssu72 is a highly conserved homologue of yeast Ssu72, a CTD phosphatase and a component of the polyadenylation/ termination machinery. The human Ssu72 is located on Chromosome 1p36 and seems to represent a single gene. It was identified as a pRb binding factor and was also shown to interact with TFIIB and yeast PTA1. Rabbit polyclonal antibodies were raised against SSU72 fusion protein. The ABs recognize a single band of ~30 Kda on immunoblots of various human cell lines but do not work well on mouse tissues.
Concentration Lot specific
General Readings
  1. St-Pierre B, Liu X, Kha LC, Zhu X, Ryan O, Jiang Z, et al. Conserved and specific functions of mammalian ssu72. Nucleic Acids Res. 2005 Jan 19;33(2):464-77. Print 2005. PubMed PMID: 15659578. (Free PMC Article available, 8 images available)
  2. Krishnamurthy, S., et al. Ssu72 is an RNA polymerase II CTD phosphatase Mol. Cell 2004, 14, 387 - 394
  3. Steinmetz EJ, Brow DA. Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcription. Mol Cell Biol. 2003 Sep;23(18):6339-49. PubMed PMID: 12944462. (Free PMC Article available, 5 images available)
Storage The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
Phosphate buffered saline with 0.08% sodium azide
Liquid purified IgG
This antibody reacts to SURF1.

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