SP6280P Survivin (CT) antibody

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Rabbit anti Mouse Survivin (CT)


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  • SP6280P

Product Description for Survivin (CT)

Rabbit anti Mouse Survivin (CT).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Survivin (CT)

Product Category Primary Antibodies
Quantity 50 µg
Synonyms Api4, Epr1, IAP4
Presentation Aff - Purified
Reactivity Ms
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer AnaSpec

Datasheet Extract

Synthetic peptide corresponding to amino acids near the C-terminus of mouse Survivin
GenBank Accession No. NP_033819
Application Western Blot: 2.5 to 5.0 µg/ml.
Positive Control: Mouse spleen tissue lysate.
Background Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP (1-3). Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas (1, 3).
Concentration 0.2 mg/ml
General Readings
  1. Ambrosini, G. et al. Nat. Med. 3, 917 (1997).
  2. Li, F. et al. Nature 396, 580 (1998).
  3. Kobayashi, K. et al. Proc. Natl. Acad. Sci. USA 96, 1457 (1999).
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Immunoaffinity chromatography
Buffer System:
Supplied in 1X PBS containing 0.02 % Sodium Azide.
Liquid Ig fraction
Aff - Purified
This antibopdy is specific for Survivin (C-Term).

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