discontinued

GTX23344 SynGAP antibody

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0.1 mg / €380.00

Quick Overview

Rabbit anti Mouse, Rat SynGAP

Product Description for SynGAP

Rabbit anti Mouse, Rat SynGAP.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for SynGAP

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Ms, Rt
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Fusion protein of a recombinant fragment, amino acids 947-1167, of rat SynGAP.
Application ICC, WB
Background Synaptic Ras GTPase Activating Protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain. SynGAP has been shown to be a major component of postsynaptic density and associates with post synaptic density 95 kDa (PSD-95), a synaptic scaffold protein, and synaptic N-methyl-D-aspartate (NMDA) receptors. SynGAP Ras-GTPase activity has also been shown to be inhibited by phosphorylation by CaM kinase II, another abundant protein located in the postsynaptic density. It has been proposed that SynGAP may function as a negative regulator of MAP Kinase activation in the absence of active NMDA receptors.
Concentration 1 mg/ml
Storage Upon receipt - Keep as concentrated solution. Aliquot and store at -20
Format
Purification:
Immunogen affinity purified
Buffer System:
PBS, 1 mg/ml BSA, 0.05% sodium azide
Purity:
Immunogen affinity purified
State:
Liquid
Aff - Purified
Specificity
Specificity:
Cross-reacts with Rat and Mouse. Not yet tested in other species.

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