NB100-64273 T-Cell Receptor TCR alpha/beta antibody

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Mouse anti Human T-Cell Receptor TCR alpha/beta BMA031


Product Description for T-Cell Receptor TCR alpha/beta

Mouse anti Human T-Cell Receptor TCR alpha/beta BMA031.
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for T-Cell Receptor TCR alpha/beta

Product Category Primary Antibodies
Quantity 0.05 mg
Presentation FITC
Reactivity Hu
Applications F
Clonality Monoclonal
Clone BMA031
Host Mouse
Isotype IgG2b
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Isotype control SM12F
Application flow cytometry / FACS analysis
Background The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain.
T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Whole Antisera
Whole Antisera
Human. Not yet tested in other species.

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