AM33019PU-N T Cell Receptor (TCR) gamma/delta antibody

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0.1 mg / €340.00
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Mouse anti Human T Cell Receptor (TCR) gamma/delta 11F2


Product Description for T Cell Receptor (TCR) gamma/delta

Mouse anti Human T Cell Receptor (TCR) gamma/delta 11F2.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Flow Cytometry, Immunoprecipitation, Frozen Sections.

Properties for T Cell Receptor (TCR) gamma/delta

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms T-Cell Receptor delta, T-Cell Receptor gamma, T-Cell Receptor gamma delta, TCRD, TCRG
Presentation Purified
Reactivity Hu
Applications C, E, F, IP
Clonality Monoclonal
Clone 11F2
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Derived by fusion of SP2/0-Ag14 mouse myeloma cells with spleen cells from a Balb/C mice immunized with protein A-Sepharose/anti-CD3 antigen complex.
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application ELISA.
Flow cytometry.
Immunohistochemistry on Frozen sections.
Background Two types of T cell antigen receptors (TCRs) are now known, the α/β, and the γ/δ heterodimer, which are expressed at the cell surface in association with the CD3 molecular complex. TCR-γ can occur in either disulphide-linked or non-disulphide-linked forms. The γ/δ-TCR is present on a minor subset of T- lymphocytes in peripheral blood, thymus, spleen, and lymph nodes. In man and mouse, only a small part of the T-lymphocytes of the peripheral blood (<5%) is γ/δ. γ/δ T-lymphocytes may complement α/β T-cells in terms of antigenic specificities, functional capabilities, or sites of action within the body.
Concentration 1.0 mg/ml
General Readings
  1. Borst, J., Van Dongen, J., Bolhuis, R., Peters, P., Hafler, D., De Vries, E., Van de Griend, R. (1988). Distinct molecular forms of human T cell receptor g/d detected on viable T cells by a monoclonal antibody. J Exp Med 167, 1626-44.
  2. Vroom TM, Scholte G, Ossendorp F, Borst J. Tissue distribution of human gamma delta T cells: no evidence for general epithelial tropism. J Clin Pathol. 1991 Dec;44(12):1012-7. PubMed PMID: 1838746. (Free PMC Article available)
  3. Bos JD, Teunissen MB, Cairo I, Krieg SR, Kapsenberg ML, Das PK, et al. T-cell receptor gamma delta bearing cells in normal human skin. J Invest Dermatol. 1990 Jan;94(1):37-42. PubMed PMID: 1688597.
  4. Lanier LL, Ruitenberg J, Bolhuis RL, Borst J, Phillips JH, Testi R. Structural and serological heterogeneity of gamma/delta T cell antigen receptor expression in thymus and peripheral blood. Eur J Immunol. 1988 Dec;18(12):1985-92. PubMed PMID: 2975598.
  5. Lanier LL, Serafini AT, Ruitenberg JJ, Cwirla S, Federspiel NA, Phillips JH, et al. The gamma T-cell antigen receptor. J Clin Immunol. 1987 Nov;7(6):429-40. PubMed PMID: 3320076.
  6. Testi R, Lanier LL. Functional expression of CD28 on T cell antigen receptor gamma/delta-bearing T lymphocytes. Eur J Immunol. 1989 Jan;19(1):185-8. PubMed PMID: 2537735.
  7. Lanier LL, Federspiel NA, Ruitenberg JJ, Phillips JH, Allison JP, Littman D, et al. The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. J Exp Med. 1987 Apr 1;165(4):1076-94. PubMed PMID: 2435832. (Free PMC Article available)
  8. Voogt PJ, Falkenburg JH, Fibbe WE, Veenhof WF, Hamilton M, Van Krimpen BA, et al. Normal hematopoietic progenitor cells and malignant lymphohematopoietic cells show different susceptibility to direct cell-mediated MHC-non-restricted lysis by T cell receptor-/CD3-, T cell receptor gamma delta+/CD3+ and T cell receptor-alpha beta+/CD3+ lymphocytes. J Immunol. 1989 Mar 1;142(5):1774-80. PubMed PMID: 2521886.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
0.09% Sodium Azide
Liquid purified IgG fraction
Species Reactivity
Species reactivity (tested):
This Antibody clone 11F2 recognizes all molecular forms of the gamma/delta T-cell receptor (TCR) desribed so far.

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