AM39063SU-N T Cell Receptor (TCR) V beta 16 antibody

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1 ml / €240.00
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Mouse anti Rat T Cell Receptor (TCR) V beta 16 HIS42


Product Description for T Cell Receptor (TCR) V beta 16

Mouse anti Rat T Cell Receptor (TCR) V beta 16 HIS42.
Presentation: Supernatant
Product is tested for Immunocytochemistry/Immunofluorescence, Frozen Sections, Immunoprecipitation.

Properties for T Cell Receptor (TCR) V beta 16

Product Category Primary Antibodies
Quantity 1 ml
Synonyms TCR V beta-16, TCR Vb16
Presentation Supernatant
Reactivity Rt
Applications C, ICC/IF, IP
Clonality Monoclonal
Clone HIS42
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Application Flow cytometry.
Immunohistochemistry on frozen sections.
Background The subpopulation of HIS 42 positive T cells contains both CD4 and CD8 positive cells, in
the same ratio as found in the peripheral T cell population. When bound to Sepharose
beads, HIS 42 induces T cell proliferation in the presence of IL-2. In contrast to lymph node
T cells a number of thymocytes are found to express HIS 42 only in the cytoplasm or
together with membrane expression. Most bright HIS 42 surface labelled thymocytes are
also positive for MRC OX-44, a marker predominantly identifying mature thymocytes.
General Readings J. Kampinga et al. Thymocyte differentiation and thymic micro-environment development in the fetal rat thymus: an immunological approach. In: Thymus Update 3. The role of the thymus in tolerance induction. Eds. M.D. Kendall and M.A. Ritter. Harwood Academic Publishers GmbH, Switzerland (1990)
J. Kampinga et al. A monoclonal antibody to a determinant of the rat Tcell antigen receptor expressed by a minor subset of T cells. Int. Immunol. 1, 289, (1989)
Storage Store undiluted at 2-8°C.
Liquid cell culture supernatant containing 0.09% sodium azide
Species Reactivity
Species reactivity (tested):
The antibody reacts with Vbeta16 T-cell receptor; it recognizes subpopulations of peripheral CD4+ T cells and CD8+ T cells, intestinal lymphocytes and thymocytes.
HIS42 monoclonal antibody induces IL-2 dependent T cell mitogenesis.

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