GTX76195 T Cell Receptor (TCR) V beta 16 antibody

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1 ml / €300.00

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Mouse anti Rat T Cell Receptor (TCR) V beta 16 HIS42


Product Description for T Cell Receptor (TCR) V beta 16

Mouse anti Rat T Cell Receptor (TCR) V beta 16 HIS42.
Presentation: Supernatant
Product is tested for Frozen Sections, Immunoprecipitation, Flow Cytometry.

Properties for T Cell Receptor (TCR) V beta 16

Product Category Primary Antibodies
Quantity 1 ml
Synonyms TCR V beta-16.1, TCR Vb16.1
Presentation Supernatant
Reactivity Rt
Applications C, F, IP
Clonality Monoclonal
Clone HIS42
Host Mouse
Isotype IgG2b
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

PVG RT7.2 Rat Thymocytes
Application FACS, IHC-Fr, IP
Background Detects a minor subset of T cells. The subpopulation of HIS 42 positive T cells contains both CD4 and CD8 positive cells, in the same ratio as found in the peripheral T cell population. When bound to Sepharose beads, HIS 42 induces T cell proliferation in the presence of IL-2. In contrast to lymph node T cells a number of thymocytes are found to express HIS 42 only in the cytoplasm or together with membrane expression. Most bright HIS 42 surface labelled thymocytes are also positive for MRC OX-44, a marker predominantly identifying mature thymocytes. SDS PAGE analysis of the membrane molecules immunoprecipitated by HIS 42 shows a band at 85kD. On reduction it separates to two bands at 35 kD and 48kD. From this data it is concluded that HIS 42 is directed against a determinant on the rat T cell receptor, which is common to a small number of T cells. Preliminary data suggests that the determinant is found on the beta chain, associated with the Vb16.1 gene product.
Storage Keep as concentrated solution. Store at 4
Buffer System:
Phosphate-buffered saline, containing 0.09% sodium azide
Not yet tested in other species

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