NB500-520 T Cell Receptor (TCR) V beta 5 antibody

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0.1 mg / €340.00
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Mouse anti Human T Cell Receptor (TCR) V beta 5 MEM-262

NB500-520

Product Description for T Cell Receptor (TCR) V beta 5

Mouse anti Human T Cell Receptor (TCR) V beta 5 MEM-262.
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Functional assay, Immunoprecipitation, Western blot / Immunoblot.

Properties for T Cell Receptor (TCR) V beta 5

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms TCR V beta-5, TCR Vb5
Presentation Aff - Purified
Reactivity Hu
Applications F, FN, IP, WB
Clonality Monoclonal
Clone MEM-262
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Human thymoma cell line HPB-ALL.
Add. information Research Areas: Cancer, Immunology
Application flow cytometry / FACS analysis, immunoprecipitation, Western Blot, flow cytometry / FACS analysis, immunoprecipitation, Western Blot Uniquely recognizes denatured TCR beta chains under the conditions of Western blotting. Optimal dilutions and concentrations should be determined by the end user., flow cytometry / FACS analysis, immunoprecipitation, Western Blot
Background T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. The Vß5 TCR is a variant of the TCR ß chain. It belongs to Ig superfamily and is expressed by a subset of peripheral blood T cells and some T cell clones. TCR Vß5 has been reported to recognize some staphylococcus bacterial superantigens.
Concentration 1 mg/ml
General Readings This product has been used in:Pavlistova D et al. A novel monoclonal reagent recognizing native and denatured Vbeta5.3-related chains of human T cell receptor. Immunol Lett 88:105-8 (2003). PubMed PMID: 12880678
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Format
Purification:
Affinity purified
Buffer System:
15mM Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
The recognizes beta chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells. This subset is larger than that recognized by other V(beta5.3)-specific antibodies.
Species:
Human

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