GTX41029 T Cell Receptor (TCR) V gamma 3 antibody

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0.1 mg / €320.00

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Hamster anti Mouse T Cell Receptor (TCR) V gamma 3 536


Product Description for T Cell Receptor (TCR) V gamma 3

Hamster anti Mouse T Cell Receptor (TCR) V gamma 3 536.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Flow Cytometry.

Properties for T Cell Receptor (TCR) V gamma 3

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms TCR V gamma-3, TCR Vg3
Presentation Purified
Reactivity Ms
Applications F, ICC/IF, IP
Clonality Monoclonal
Clone 536
Host Hamster
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen sequence information is commercially sensitive
Application FACS, H, IF, IP
Background T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable) , J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangment of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia.
Concentration 0.5 mg/ml
Storage Keep as concentrated solution. Store at 4
Protein G purified
Buffer System:
0.01M PBS. pH 7.2 containing 1% BSA and 0.09% sodium azide
Protein G purified
Mouse - Not yet tested in other species

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