AM05100PU-N T Cell Receptor (TCR) Vb 2 antibody

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0.1 mg / €580.00

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Mouse anti Human T Cell Receptor (TCR) Vb 2 MPB2D5


Product Description for T Cell Receptor (TCR) Vb 2

Mouse anti Human T Cell Receptor (TCR) Vb 2 MPB2D5.
Presentation: Purified
Product is tested for Flow Cytometry.

Properties for T Cell Receptor (TCR) Vb 2

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms TCR V beta-2, TCR Vb2
Presentation Purified
Reactivity Hu
Applications F
Clonality Monoclonal
Clone MPB2D5
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Human T-cell line
Application T-cell repertoire research studies in normal and pathological situations.
Superantigenic stimulation of T cells; V beta-2 is for example the target of TSST1.
Flow cytometry: 2µg/5x10e5 cells/test or 100µl whole blood.
General Readings
  1. Cornélis F, Pile K, Loveridge J, Moss P, Harding R, Julier C, et al. Systematic study of human alpha beta T cell receptor V segments shows allelic variations resulting in a large number of distinct T cell receptor haplotypes. Eur J Immunol. 1993 Jun;23(6):1277-83. PubMed PMID: 8500523.
  2. Wei S, Charmley P, Robinson MA, Concannon P. The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics. 1994;40(1):27-36. PubMed PMID: 8206523.
  3. Clarke, G.R., et al., (1994), Bimodal distribution of V beta-2+CD4+ T cells in human peripheral blood, Eur. J. Immunol., 24, 837 - 842.
  4. Posnett, D.N., et al., (1996), First human TcR monoclonal antibody workshop, The Immunologist, 4, (1), 5 - 8.
  5. Imberti, L., et al., (1991), Selective depletion in HIV infection of T cells that bear specific T cell receptor V beta sequences, Science, 254, 860 - 862.
  6. Choi, Y., et al., Interaction of staphylococcus aureus toxin superantigens with human T cells, Proc. Natl. Acad. Sci., USA, 86, 8941 - 8945.
Storage Prior to reconstitution store at 2-8°C.
Following reconstitution store the antibody at -20°C.
The addition of 0.1% sodium azide is recommended for storage of the reconstituted form for up to one month at 2 - 8°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
PBS containing 1mg/ml BSA
Lyophilized purified Ig
Restore with 0.5ml of distilled water
This antibody reacts to the variable beta-2 chain of the T-cell receptor. The antibody recognizes all alleles of the single member of V beta-2 family (described in) also called TCRBV2S1 according to the nomenclature from Wei et al. This antibody has been further characterized by cell sorting on PBL using this monoclonal antibody followed by analysis of sorted cells by molecular biology. This antibody is described in ref. 3 and has been confirmed at the First Human TcR Monoclonal Antibody Workshop in San Francisco in 1995.

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