discontinued

AM05103RP-N T Cell Receptor (TCR) Vb 5.1 antibody

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50 Tests / €700.00

Quick Overview

Mouse anti Human T Cell Receptor (TCR) Vb 5.1 Immu157

AM05103RP-N

Product Description for T Cell Receptor (TCR) Vb 5.1

Mouse anti Human T Cell Receptor (TCR) Vb 5.1 Immu157.
Presentation: Phyco
Product is tested for Flow Cytometry.

Properties for T Cell Receptor (TCR) Vb 5.1

Product Category Primary Antibodies
Quantity 50 Tests
Synonyms TCR V beta-5.1, TCR Vb5.1
Presentation Phyco
Reactivity Hu
Applications F
Clonality Monoclonal
Clone Immu157
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Murine T-cell hybridoma transfected with human V beta 5.1 gene segment
Application Flow cytometry: 20µl/5 x 10e5 cells/test or 100µl whole blood.
Concentration 4,0 µg/ml
General Readings
  1. Wei S, Charmley P, Robinson MA, Concannon P. The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics. 1994;40(1):27-36. PubMed PMID: 8206523.
  2. Kimura N, Toyonaga B, Yoshikai Y, Triebel F, Debre P, Minden MD, et al. Sequences and diversity of human T cell receptor beta chain variable region genes. J Exp Med. 1986 Sep 1;164(3):739-50. PubMed PMID: 3755748. (Free PMC Article available)
  3. Concannon, P., et al., Diversity and structure of human T-cell receptor beta chain variable region genes, 1986, Proc. Natl. Acad. Sci., USA, 83, 6598 - 6602.
  4. Leiden, J.M., et al., Generation of diversity of the beta chain of the human T lymphocyte receptor for antigen, Proc. Natl. Acad. Sci., USA, 83, 4456 - 4460.
  5. Posnett, D.N., et al., First Human TcR Monoclonal Antibody Workshop, 1996, The Immunologist, 4, (1), 5 - 8.
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
Shelf life: one year from despatch.
Format
Label:
Phycoerythrin
Phyco
Buffer System:
PBS containing 2mg/ml BSA and 0,09% sodium azide
State:
Liquid purified Ig
Specificity
Specificity:
This antibody reacts to variable beta 5.1 chain of the T-cell receptor (TCR), also called TCRBV5S1 according to the nomenclature of Wei, et al. This antibody recognizes the HBP51 sequence of the multimembered V beta 5 subfamily. It does not recognize V beta 5.2 (PL2.5 sequence) and V beta 5.3 (12A1 sequence). The specificity of this antibody has been confirmed at the First Human TcR Monoclonal Antibody Workshop in San Francisco in 1995.
Species:
Human.

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