AM05103RP-N T Cell Receptor (TCR) Vb 5.1 antibody

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Mouse anti Human T Cell Receptor (TCR) Vb 5.1 Immu157


Product Description for T Cell Receptor (TCR) Vb 5.1

Mouse anti Human T Cell Receptor (TCR) Vb 5.1 Immu157.
Presentation: Phyco
Product is tested for Flow Cytometry.

Properties for T Cell Receptor (TCR) Vb 5.1

Product Category Primary Antibodies
Quantity 50 Tests
Synonyms TCR V beta-5.1, TCR Vb5.1
Presentation Phyco
Reactivity Hu
Applications F
Clonality Monoclonal
Clone Immu157
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Murine T-cell hybridoma transfected with human V beta 5.1 gene segment
Application Flow cytometry: 20µl/5 x 10e5 cells/test or 100µl whole blood.
Concentration 4,0 µg/ml
General Readings
  1. Wei S, Charmley P, Robinson MA, Concannon P. The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics. 1994;40(1):27-36. PubMed PMID: 8206523.
  2. Kimura N, Toyonaga B, Yoshikai Y, Triebel F, Debre P, Minden MD, et al. Sequences and diversity of human T cell receptor beta chain variable region genes. J Exp Med. 1986 Sep 1;164(3):739-50. PubMed PMID: 3755748. (Free PMC Article available)
  3. Concannon, P., et al., Diversity and structure of human T-cell receptor beta chain variable region genes, 1986, Proc. Natl. Acad. Sci., USA, 83, 6598 - 6602.
  4. Leiden, J.M., et al., Generation of diversity of the beta chain of the human T lymphocyte receptor for antigen, Proc. Natl. Acad. Sci., USA, 83, 4456 - 4460.
  5. Posnett, D.N., et al., First Human TcR Monoclonal Antibody Workshop, 1996, The Immunologist, 4, (1), 5 - 8.
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Buffer System:
PBS containing 2mg/ml BSA and 0,09% sodium azide
Liquid purified Ig
This antibody reacts to variable beta 5.1 chain of the T-cell receptor (TCR), also called TCRBV5S1 according to the nomenclature of Wei, et al. This antibody recognizes the HBP51 sequence of the multimembered V beta 5 subfamily. It does not recognize V beta 5.2 (PL2.5 sequence) and V beta 5.3 (12A1 sequence). The specificity of this antibody has been confirmed at the First Human TcR Monoclonal Antibody Workshop in San Francisco in 1995.

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